The Role of Magnetic Resonance Imaging in Evaluating Tuberculoma and Neurocysticercosis: Differentiation Using Magnetization Transfer Ratio in a Tertiary Care Hospital (Code-T0144)
Keywords:
Magnetic Resonance Imaging, Tuberculoma, Neurocysticercosis, Magnetization Transfer Ratio, Intracranial Lesions, Diagnostic Accuracy.Synopsis
Introduction: Tuberculoma and neurocysticercosis (NCC) are common causes of intracranial lesions in endemic regions, often presenting with overlapping clinical and radiological features. Accurate differentiation is crucial for appropriate treatment. Magnetic Resonance Imaging (MRI), including magnetization transfer ratio (MTR) analysis, has emerged as a valuable tool in differentiating these lesions.
Aims and Objectives:
Aim:
Role of magnetic resonance imaging in evaluation of tuberculoma and neurocysticercosis and differentiating between them using magnetisation transfer ratio in a tertiary care hospital
Objective:
- To identify and evaluate MRI characteristics of Tuberculoma and Neurocysticercosis lesions.
- To differentiate between the rings enhances lesions of Tuberculoma and Neurocysticercosis using Magnetisation Transfer Ratio.
Methods: A prospective study was conducted involving patients presenting with intracranial lesions suspected to be tuberculoma or NCC. All participants underwent detailed clinical evaluation and MRI scans, including MTR imaging. Lesions were analyzed for MTR values, morphological characteristics, and contrast enhancement patterns. Final diagnoses were confirmed through histopathology, serology, or clinical response to therapy. Statistical analysis was performed to assess the sensitivity, specificity, and diagnostic accuracy of MTR in differentiating the two conditions.
Results: MTR values were significantly higher in tuberculomas compared to NCC lesions (p < 0.05). Tuberculomas demonstrated homogenous enhancement with higher perilesional edema, while NCC exhibited ring enhancement with scolex visualization. MTR analysis achieved a diagnostic accuracy of 89%, sensitivity of 91%, and specificity of 87% in distinguishing between the two.
Conclusion: MRI with MTR analysis is a reliable and non-invasive tool for differentiating tuberculoma and NCC, aiding in accurate diagnosis and appropriate treatment decisions.
Keywords: Magnetic Resonance Imaging, Tuberculoma, Neurocysticercosis, Magnetization Transfer Ratio, Intracranial Lesions, Diagnostic Accuracy.
