The Role of 3-Tesla MRI in Diagnosing and Staging Suspected Endometrial Carcinoma: Correlation with Histopathology (Code-T0180)

Introduction: Endometrial carcinoma is the most common gynecological malignancy, often diagnosed in postmenopausal women. Accurate diagnosis and staging are essential for optimal treatment planning. Magnetic Resonance Imaging (MRI), particularly 3 Tesla (3T) MRI, offers superior soft tissue contrast and spatial resolution, making it a valuable tool in assessing tumor extent. This study evaluates the efficacy of 3T MRI in diagnosing and staging endometrial carcinoma and its correlation with histopathology.

Aims and Objectives: The study aims to determine the diagnostic accuracy of 3T MRI in endometrial carcinoma and to correlate imaging findings with histopathological results for tumor staging and characterization.

Methods: A prospective study was conducted on patients with clinically or sonographically suspected endometrial carcinoma. All patients underwent 3T MRI followed by histopathological examination of surgical specimens. MRI findings, including tumor size, depth of myometrial invasion, and lymph node status, were compared with histopathology results to evaluate sensitivity, specificity, and accuracy.

Results: 3T MRI demonstrated high sensitivity (92%) and specificity (89%) in detecting myometrial invasion and accurate lymph node assessment. The imaging findings correlated significantly with histopathological results (p<0.05). Tumor staging by MRI was consistent with histopathology in 88% of cases.

Conclusion: 3T MRI is a reliable modality for diagnosing and staging endometrial carcinoma, offering excellent correlation with histopathology. It plays a critical role in preoperative evaluation and treatment planning.

Keywords: Endometrial carcinoma, 3 Tesla MRI, Tumor staging, Myometrial invasion, Diagnosis, Histopathology correlation.