An Observational Study on Serum Ferritin Levels, C - reactive protein, and HbA1c Levels in Patients of Type 2 Diabetes Mellitus Attending a Tertiary Healthcare Centre in Northeast as a Marker for Glycaemic Control (Code-T0236)

Introduction: Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance and persistent hyperglycemia. Chronic low-grade inflammation plays a crucial role in the pathogenesis and complications of T2DM. Serum ferritin and C-reactive protein (CRP) are markers of inflammation and have been associated with glycemic control, as reflected by HbA1c levels. This study aims to evaluate the correlation between serum ferritin, CRP, and HbA1c levels in T2DM patients.

Aims and Objectives:

1. To analyze the correlation between serum ferritin and CRP levels with HbA1c in T2DM patients.
2. To assess the potential of serum ferritin and CRP as biomarkers for glycemic control in T2DM.

Methods: This hospital-based observational study will be conducted at Tezpur Medical College and Hospital, Assam, over one year. The study will include T2DM patients aged above 30 years attending the outpatient department. Venous blood samples will be collected from eligible participants and analyzed for serum ferritin, CRP, and HbA1c levels. Statistical analysis will be performed using SPSS 23.0 to determine correlations.

Results: The data will be subjected to statistical analysis to determine the association between serum ferritin, CRP, and HbA1c levels. The findings will establish whether these inflammatory markers can serve as reliable indicators of glycemic control.

Conclusion: This study aims to contribute to the understanding of inflammation in T2DM and its impact on glycemic control. If a significant correlation is established, serum ferritin and CRP could serve as potential biomarkers for monitoring diabetes management.

Keywords: Type 2 Diabetes Mellitus, HbA1c, Serum Ferritin, C-Reactive Protein, Glycemic Control, Inflammation.