Prevalence of Depression in Stroke Survivors and Its Relationship with Lesion Location and Duration of Stroke Onset in Post-Stroke Depression (Code-T0278)
Keywords:
Post-stroke depression, Stroke survivors, Lesion location, Depression prevalence, Stroke onset, Neuroimaging.Synopsis
Introduction: Depression is a common and debilitating condition among stroke survivors, affecting their recovery and quality of life. The relationship between the site of the brain lesion and the duration of stroke onset on the development of post-stroke depression (PSD) remains an area of ongoing research. Understanding these factors is crucial for improving treatment strategies and outcomes for stroke patients.
Aims and Objective: This study aims to estimate the prevalence of depression in stroke survivors and investigate the relationship between lesion site and duration of stroke onset with PSD.
Methods: A cross-sectional study was conducted with 150 stroke survivors who were assessed for depression using the Hamilton Depression Rating Scale (HDRS). Neuroimaging data were reviewed to identify the lesion site, and the duration between stroke onset and depression diagnosis was recorded. Statistical analyses were performed to evaluate the relationship between these variables and the presence of depression.
Results: The prevalence of depression in stroke survivors was found to be 45%. Significant associations were observed between the site of the lesion, especially in the frontal and temporal lobes, and higher rates of depression. Additionally, patients with a longer duration from stroke onset to depression diagnosis had a higher likelihood of developing PSD. Lesions in specific brain regions were found to influence both the severity and onset of depression.
Conclusion: Post-stroke depression is highly prevalent among stroke survivors, with lesion location and the time since stroke onset playing significant roles in its development. Early identification and tailored interventions based on lesion site may help mitigate the impact of depression in these patients.
Keywords: Post-stroke depression, Stroke survivors, Lesion location, Depression prevalence, Stroke onset, Neuroimaging.
