Evaluation of the Correlation Between Neutrophil-to-Lymphocyte Ratio and Myocardial Infarction Severity in Patients from Central India (Code-T0285)

Introduction: Myocardial infarction (MI) is a leading cause of morbidity and mortality worldwide. Inflammatory markers play a crucial role in the pathogenesis and progression of MI. The neutrophil-to-lymphocyte ratio (NLR) is a simple, cost-effective biomarker that reflects systemic inflammation and has been associated with cardiovascular risk and prognosis. Understanding its correlation with MI severity could aid in early risk stratification and management.

Aims and Objectives:

Aim- to evaluate correlation between neutrophil to lymphocyte ratio and severity of myocardial infarction in patients in central india

Objective: The objective of this study is to investigate the utility of the neutrophil-to-lymphocyte ratio (NLR) as a biomarker in myocardial infarction (MI), with a focus on its prognostic value for predicting adverse outcomes

Methods: A prospective observational study will be conducted on MI patients admitted to a tertiary care hospital. Complete blood count parameters, including neutrophil and lymphocyte counts, will be analyzed at admission. MI severity will be assessed using clinical criteria, ECG findings, cardiac biomarkers, and echocardiography. Correlation between NLR and MI severity will be evaluated using appropriate statistical methods.

Results: It is anticipated that higher NLR values will significantly correlate with increased MI severity, larger infarct size, and poorer clinical outcomes. The study expects to establish NLR as a reliable inflammatory marker for MI prognosis.

Conclusion: NLR is a promising, readily available biomarker that may aid in the early identification of high-risk MI patients. Its integration into routine clinical assessment could enhance risk stratification and guide therapeutic interventions.

Keywords: Myocardial Infarction, Neutrophil-to-Lymphocyte Ratio, Inflammation, Biomarker, Cardiovascular Risk, Prognosis.