Evaluation of CT Coronary Calcium Score in Obese Patients (BMI ≥30) in the Indian Population (Code-T0300)

Introduction: Coronary artery calcium (CAC) is a strong predictor of cardiovascular events and is increasingly used for risk stratification in asymptomatic individuals. Obesity, a major global health concern, is strongly associated with cardiovascular diseases (CVD), diabetes, and hypertension. The assessment of CAC using computed tomography (CT) in obese individuals provides valuable insights into subclinical atherosclerosis and cardiovascular risk. However, there is limited data on CAC distribution among obese individuals in the Indian population.

Aims and Objectives

Aim

To study the difference in the distribution CT coronary calcium score (CCC) among obese.

Objective

Primary Objective:

Among adult’s obese patients (BMI >30) attending our hospital

• To study the distribution of CT coronary calcium score (CCC)
• To estimate the difference in the distribution CT coronary calcium score (CCC) among obese (BMI ≥ 30)

Secondary Objective:

• Early detection of CAD

Methods: A prospective observational study will be conducted at Apollo Hospital, Visakhapatnam, over two years. A total of 100 obese individuals (BMI ≥ 30) will undergo coronary calcium scoring using a 64-row CT scanner. Lipid profiles, fasting blood glucose, HbA1c, and other relevant biochemical markers will be analyzed. Statistical comparisons will be made between diabetic and non-diabetic groups and among patients with varying cardiovascular risk profiles. Data will be analyzed using SPSS, with a significance level of p < 0.05.

Results: The study is expected to demonstrate a higher prevalence of coronary calcification in obese individuals, with increased CAC scores correlating with diabetes, hypertension, and dyslipidemia.

Conclusion:Early detection of subclinical atherosclerosis using CAC scoring in obese individuals can aid in personalized cardiovascular risk assessment and preventive strategies.

Keywords: Coronary Artery Calcium, Obesity, Cardiovascular Risk, Computed Tomography, Atherosclerosis, Risk Stratification