A Prospective Study on the Correlation Between Bone Mineral Density Changes in Patients Undergoing Total Knee Replacement Surgery: Pre and Postoperative DEXA Scan Analysis (Code-T0029)

Authors

Synopsis/Protocol/Thesis

Keywords:

Bone Mineral Density, Total Knee Replacement, DEXA Scan, Osteoarthritis, Postoperative Recovery, Bone Health.

Synopsis

Introduction: Total knee replacement (TKR) is a widely performed procedure for patients with advanced knee osteoarthritis. While the focus is primarily on improving joint function and pain relief, changes in bone mineral density (BMD) around the knee are often overlooked. BMD alterations, especially postoperatively, may impact patient recovery and long-term outcomes. This study aims to evaluate BMD changes before and after TKR using dual-energy X-ray absorptiometry (DEXA) scans.

Aims & Objective: To investigate the correlation between changes in BMD in patients undergoing TKR, comparing preoperative and postoperative measurements using DEXA scans, and to assess the clinical significance of these changes.

Methods: This prospective study included 65 patients undergoing primary TKR. BMD was measured at the femoral neck and lumbar spine preoperatively and 6 months postoperatively using DEXA scans. Data were analyzed for changes in BMD values and correlated with postoperative functional outcomes, pain scores, and complications.

Results: The study found significant decreases in BMD around the knee postoperatively, especially in the femoral neck region. These changes were more pronounced in patients with longer preoperative duration of osteoarthritis and higher body mass index. A negative correlation was observed between BMD loss and functional recovery, particularly in patients who exhibited greater bone loss.

Conclusion: TKR is associated with significant changes in BMD, with most alterations occurring postoperatively. Regular monitoring of BMD through DEXA scans may provide valuable insights into bone health and guide the development of postoperative management strategies aimed at enhancing recovery and minimizing complications.

Keywords: Bone Mineral Density, Total Knee Replacement, DEXA Scan, Osteoarthritis, Postoperative Recovery, Bone Health.

Published

December 27, 2024

How to Cite

A Prospective Study on the Correlation Between Bone Mineral Density Changes in Patients Undergoing Total Knee Replacement Surgery: Pre and Postoperative DEXA Scan Analysis (Code-T0029). (2024). Medical Thesis. https://medicalthesis.org/index.php/mt/catalog/book/31