Presenting to a tertiary care center in known cases of copd with special emphasis on diastolic dysfunction (Code-T0323)

Authors

Synopsis/Protocol/Thesis

Keywords:

COPD, Cardiovascular Disease, Diastolic Dysfunction, Pulmonary Function, Echocardiography, Heart Failure.

Synopsis

Introduction: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity 
and mortality worldwide, often associated with cardiovascular diseases (CVDs). COPD patients 
frequently develop ischemic heart disease, congestive heart failure, and arrhythmias. Diastolic 
dysfunction is a commonly reported cardiac complication in COPD, contributing to heart failure 
with preserved ejection fraction. This study aims to assess the prevalence of cardiovascular 
complications, particularly diastolic dysfunction, in COPD patients. 
Aims and Objectives 
1. The primary outcome of this study is was to investigate the association between COOD 
and the prevalence of one type of common CVD. 
2. To investigate the prognostic value of chest x-ray, ecg and 2-d echo in patients with copd 
and heart failure. 
3. To find effective strategies that can reduce both COPD and CVD comorbidities to 
improve the prognosis of COPD patients and reduce their cardiovascular mortality. 
Methods: A cross-sectional observational study was conducted at Civil Hospital, Rajkot, 
involving 120 COPD patients diagnosed based on GOLD criteria. Patients underwent clinical 
evaluation, pulmonary function tests, and echocardiographic assessment. The severity of COPD 
was classified, and cardiovascular parameters were analyzed for statistical significance. 
Results: The study found an increasing trend in left ventricular diastolic dysfunction (LVDD) 
with worsening COPD severity, though statistical analysis (p > 0.05) indicated no significant 
correlation. Additionally, chest X-ray, ECG, and 2D echo showed limited predictive value for 
CVD in COPD patients. Multidisciplinary management, including smoking cessation, 
pharmacotherapy, and pulmonary rehabilitation, emerged as key strategies for reducing 
cardiovascular risk. 
Conclusion: While LVDD prevalence rises with COPD severity, it may not be solely attributed 
to COPD progression. A comprehensive diagnostic approach, integrating biomarkers and 
advanced imaging, is essential for early detection and management of cardiovascular 
complications in COPD patients. 
Keywords: COPD, Cardiovascular Disease, Diastolic Dysfunction, Pulmonary Function, 
Echocardiography, Heart Failure.

Published

April 22, 2025

How to Cite

Presenting to a tertiary care center in known cases of copd with special emphasis on diastolic dysfunction (Code-T0323). (2025). Medical Thesis. https://medicalthesis.org/index.php/mt/catalog/book/330