Study of ACUITY PCI Score in Non-ST Segment Elevation Myocardial Infarction Patients Undergoing PCI and Its Comparison with TIMI, GRACE, and SYNTAX Scores (CodeT0342)

Introduction: Non-ST segment elevation myocardial infarction (NSTEMI) is a critical 
cardiovascular condition requiring precise risk stratification for optimal patient management. 
The ACUITY PCI score is a novel risk assessment tool designed to predict mortality and 
reinfarction in NSTEMI patients undergoing percutaneous coronary intervention (PCI). This 
study evaluates the prognostic accuracy of the ACUITY PCI score and compares it with 
established risk scores—TIMI, GRACE, and SYNTAX. 
Aims and Objectives:  
Aim:  
To assess the ACUITY PCI score in non -ST-segment elevation myocardial infarct ion in 
patients receiving percutaneous coronary intervention. 
Objective: 
• To assess the validity of the ACUITY PCI Score for the predict ion of risk of death or 
reinfarction at the end of 1 year. 
• The prognostic accuracy of the ACUITY PCI score will be compared with GRACE, TIMI and 
SYNTAX risk scores . 
Methods: A prospective observational study was conducted at SRM Medical College Hospital, 
Chennai, over 18 months. A total of 100 NSTEMI patients undergoing PCI were enrolled. 
ACUITY PCI, TIMI, GRACE, and SYNTAX scores were calculated for each patient. Statistical 
analysis, including receiver operating characteristic (ROC) curve analysis, was performed to 
assess the predictive accuracy of these scores. 
Results: The ACUITY PCI score demonstrated superior prognostic accuracy, with an area under 
the curve (AUC) of 0.99, sensitivity of 90.91%, and specificity of 96.63%. In comparison, 
GRACE, TIMI, and SYNTAX scores had lower predictive accuracy, with AUC values of 0.79, 
0.69, and 0.51, respectively. 
Conclusion: The ACUITY PCI score outperformed TIMI, GRACE, and SYNTAX in predicting 
one-year mortality or reinfarction in NSTEMI patients undergoing PCI. Its incorporation into 
clinical practice can enhance risk stratification and improve patient management. 
Keywords: NSTEMI, ACUITY PCI score, TIMI score, GRACE score, SYNTAX score, 
percutaneous coronary intervention.