Clinical Profile and Short-Term Outcomes of Pediatric Status Epilepticus: A CrossSectional Study at a Tertiary Care Centre (Code-T0347)

Introduction: Status epilepticus (SE) is a common paediatric neurological emergency 
associated with significant morbidity and mortality. It requires rapid intervention to minimize 
adverse outcomes. The incidence is highest in children under two years, often due to 
symptomatic causes, genetic/metabolic disorders, or increased seizure susceptibility in the 
developing brain. 
Aims and Objectives:  
Aims: To assess the clinical profile and clinical outcome of children admitted with status 
epilepticus.  
Primary Objectives  
To assess the clinical features& outcome in children admitted with status epilepticus..  
Secondary Objectives  
To determine the risk factors associated with poor clinical outcomes among children admitted 
with status epilepticus.  
Methods: A cross-sectional observational study was conducted over 18 months in the 
paediatric ward and intensive care unit. Children aged 1 month to 12 years diagnosed with SE 
were included. Clinical characteristics, seizure etiology, treatment responses, and short-term 
outcomes were recorded. Data were analyzed using SPSS software. 
Results: The study included 85 children with SE. Acute symptomatic causes, including CNS 
infections and febrile seizures, were predominant. Approximately 60% of cases responded to 
benzodiazepines, while refractory SE was observed in a significant proportion. Factors such 
as prolonged seizure duration, delayed treatment, and underlying neurological conditions 
were associated with poor outcomes. Mortality was primarily linked to acute symptomatic 
etiologies. 
Conclusion: SE in children remains a critical condition requiring early identification and 
prompt management. Timely treatment reduces complications and improves outcomes. 
Preventive measures, including better management of CNS infections and febrile seizures, 
are essential. 
Keywords: Status epilepticus, paediatrics, seizure outcomes, neurological emergency, 
convulsive SE, risk factors.