Comparative Observational Study on the Prognostic Accuracy of BAP-65 and DECAF Scores in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (Code-T0361)

Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity 
and mortality worldwide, with acute exacerbations significantly impacting patient outcomes. 
Accurate prognostication in hospitalized patients remains challenging. The BAP 65 and DECAF 
scores have been developed to predict in-hospital mortality and the need for mechanical 
ventilation, but their comparative effectiveness is still under investigation. 
Aims and Objectives:  
1. To assess BAP 65 score on first, third and fifth day of admission and to monitor its 
progression. 
2. To assess DECAF score on first, third and fifth day of admission and to monitor its 
progression. 
3. To compare BAP 65 score with DECAF score in predicting need for mechanical 
ventilation and duration of hospital stay in COPD patients. 
Methods: A longitudinal observational study will be conducted over 1.5 years at the Azeezia 
Institute of Medical Sciences and Research. Eighty-five COPD patients admitted with acute 
exacerbations will be assessed using the BAP 65 and DECAF scores on the first, third, and fifth 
days of hospitalization. Statistical analysis will include repeated measures ANOVA and 
calculation of sensitivity and specificity. 
Results: The study is expected to determine whether BAP 65 or DECAF score is superior in 
predicting patient outcomes. Preliminary evidence suggests that both scores are useful, but 
further validation is needed. 
Conclusion: Establishing a more effective prognostic tool will aid clinicians in optimizing 
patient management, early intervention, and resource allocation. 
Keywords: COPD, Acute Exacerbation, BAP 65 Score, DECAF Score, Prognostic Tool, 
Mechanical Ventilation