A Study Correlating Serum Magnesium and Child Pugh Score in Liver Cirrhosis (Code-T0040)

Introduction: Cirrhosis, the end stage of chronic liver disease (CLD), results from various etiologies, including alcohol, NAFLD, hepatitis viruses, and autoimmune diseases. It involves diffuse hepatic fibrosis and regenerative nodule formation, leading to severe complications and high mortality. Magnesium is vital for physiological functions and is closely linked with liver health. This study evaluates serum magnesium levels in cirrhotic patients and their association with disease severity.

Aim & Objective: To assess the correlation of serum magnesium and severity of liver cirrhosis by using Child-Pugh score and hence prognosis of cirrhosis.

Methods: The study involves measuring serum magnesium levels in patients diagnosed with liver cirrhosis. The severity of cirrhosis is classified using the Child-Pugh score, which assesses clinical and biochemical parameters. Statistical analysis will determine the correlation between magnesium levels and cirrhosis severity.

Results: Preliminary findings suggest a significant decrease in serum magnesium levels with increasing severity of liver cirrhosis. Patients with advanced cirrhosis (Child- Pugh class B and C) exhibit lower magnesium levels compared to those with milder disease (Child-Pugh class A).

Conclusion: Serum magnesium levels are inversely correlated with the severity of liver cirrhosis. Monitoring magnesium levels could be a useful prognostic tool in cirrhotic patients, aiding in the management and treatment of the disease.

Keywords: Cirrhosis, Chronic Liver Disease, Hepatic Fibrosis, Regenerative Nodules, Serum Magnesium, Child-Pugh Score, Prognosis