Associations of A Body Shape Index, Waist-Hip Ratio, and Waist-Height Ratio with Liver, Metabolic, and Inflammatory Biomarkers Among Routine Health Check-Up Patients at a Tertiary Care Hospital in Chhattisgarh (Code –T0049)

Introduction: Obesity-related anthropometric indices such as A Body Shape Index (ABSI), Waist-Hip Ratio (WHR), and Waist-Height Ratio (WHtR) have emerged as critical markers for assessing risks of liver dysfunction, metabolic syndrome, and systemic inflammation. This study investigates the associations between these indices and liver, metabolic, and inflammatory biomarkers among individuals undergoing routine health check-ups.

Aim and Objective: To Find Out Associations of A Body Shape Index, Hip Index,Waist To Hip Ratio, Waist To Height Ratio With Liver, Metabolic and Inflammatory Biomarkers

Methods: This cross-sectional study included 250 adult patients undergoing routine health check-ups. Anthropometric measurements, including height, weight, waist, and hip circumferences, were recorded. Liver biomarkers (ALT, AST, GGT), metabolic markers (fasting glucose, lipid profile), and inflammatory markers (CRP, ESR) were analyzed. Correlation and regression analyses were performed to assess the relationships between the anthropometric indices and the biomarkers.

Results: WHR and WHtR showed significant positive correlations with elevated liver enzymes (ALT and GGT) and markers of metabolic dysfunction, including hyperglycemia and dyslipidemia (p < 0.05). ABSI was independently associated with increased CRP levels, indicating systemic inflammation. WHtR demonstrated the strongest predictive value for combined liver, metabolic, and inflammatory abnormalities. These associations persisted even after adjusting for age, sex, and BMI.

Conclusion: ABSI, WHR, and WHtR are valuable anthropometric tools for predicting liver, metabolic, and inflammatory risk profiles. WHtR, in particular, holds promise as a simple yet robust measure for routine screening in clinical settings.

Keywords: A Body Shape Index, Waist-Hip Ratio, Waist-Height Ratio, liver biomarkers, metabolic markers, inflammation.