Infection Patterns Among Patients Admitted to the Respiratory High Dependency Unit at a Tertiary Care Hospital (Code-T0054)

Introduction: Respiratory infections are a leading cause of morbidity and mortality in hospitalized patients, particularly in respiratory high dependency units (RHDU), which cater to critically ill individuals requiring intensive respiratory care. Understanding infection patterns is crucial for improving patient outcomes and infection control strategies.

Aim and Objectives

Aim

Pattern of Infection in Patient Admitted in Respiratory High Dependency Unit at Tertiary Care Hospital

Primary Objective:

High Dependency Unit Patients were assessed for - Any Bacterial or Fungal Infection in Various Biological Samples of the Patient.

Secondary Objective:

To Study the Bacterial Flora and Antibiotic Sensitivity in Patients Admitted in High Dependency Unit.

Methods: This observational study was conducted over 12 months in the RHDU of a tertiary care hospital. Data on demographics, clinical presentations, comorbidities, microbiological findings, and outcomes were collected from 150 patients with suspected infections. Specimens from respiratory secretions, blood, and urine were analyzed to identify pathogens. Statistical analyses were performed to determine infection patterns and their association with clinical outcomes.

Results: Among 150 patients, 65% had bacterial infections, 20% viral, and 15% fungal. The most common pathogens were Klebsiella pneumoniae (30%), Pseudomonas aeruginosa (25%), and Staphylococcus aureus (15%). Antibiotic resistance was observed in 40% of isolates. Patients with multi-drug-resistant infections had significantly higher mortality rates (35% vs. 20%, p<0.05). Ventilator-associated pneumonia and bloodstream infections were the most frequent complications.

Conclusion: The study highlights a high prevalence of bacterial infections and significant antibiotic resistance in the RHDU. Tailored infection control measures, early detection, and appropriate antimicrobial stewardship are essential to improve outcomes.

Keywords: Respiratory infections, RHDU, antibiotic resistance, ventilator-associated pneumonia, tertiary care, infection control.