Effect of Neodymium-doped Yttrium Aluminum Garnet (Nd:YAG) Laser Capsulotomy on Anterior Segment Parameters: A Prospective Observational Study (Code-T0089)

Authors

Synopsis/Protocol/Thesis

Keywords:

posterior capsular opacification, Nd:YAG laser, anterior chamber depth, intraocular pressure, anterior segment, optical coherence tomography.

Synopsis

Introduction: Posterior capsular opacification (PCO), the most common long-term complication following cataract surgery, significantly impairs visual acuity. Nd:YAG laser capsulotomy is a minimally invasive treatment for PCO. This study investigates its impact on anterior segment parameters.

Aims and Objective:

Aim

To evaluate the effect of Neodymium-doped Yttrium Aluminum Garnet (Nd:YAG) laser capsulotomy on anterior segment parameters.

Objectives

Primary Objective:

  • To determine changes in anterior chamber depth and angle of the anterior chamber after Nd:YAG laser capsulotomy.

Secondary Objectives:

  • To correlate the severity of PCO with change in position of IOL after Nd:YAG laser capsulotomy.
  • To determine incidence and severity of anterior chamber inflammation after Nd:YAG laser capsulotomy.
  • To correlate between energy used in Nd:YAG laser capsulotomy and size of the opening created with post-laser anterior chamber parameters.

Methods: A prospective observational study was conducted at AIIMS Bathinda, including pseudophakic patients diagnosed with PCO. Anterior segment parameters were measured preoperatively and postoperatively using anterior segment optical coherence tomography (AS-OCT). Data were analyzed with paired t-tests and repeated measures ANOVA.

Results: ACD showed a significant increase post-capsulotomy (p<0.05), attributed to posterior movement of the intraocular lens (IOL). AOD and TISA parameters also exhibited notable improvements, indicating enhanced aqueous outflow. A transient rise in IOP was observed immediately post-procedure but normalized within a week. No major complications such as retinal detachment or cystoid macular edema were reported.

Conclusion: Nd:YAG laser capsulotomy effectively restores visual function and improves anterior segment parameters with minimal risks. Monitoring and appropriate management of transient IOP elevation are crucial for optimal outcomes.

Keywords: posterior capsular opacification, Nd:YAG laser, anterior chamber depth, intraocular pressure, anterior segment, optical coherence tomography.

Published

January 7, 2025

How to Cite

Effect of Neodymium-doped Yttrium Aluminum Garnet (Nd:YAG) Laser Capsulotomy on Anterior Segment Parameters: A Prospective Observational Study (Code-T0089). (2025). Medical Thesis. https://medicalthesis.org/index.php/mt/catalog/book/90